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Background and aims
Although most opioid‐related mortality in Australia involves prescription opioids, most research to understand the impact of naloxone supply on opioid‐related mortality has focused upon people who inject heroin. We aimed to examine the cost and probable impact of up‐scaling naloxone supply to people who are prescribed opioids.
Design
Decision‐tree model. Four scenarios were...
The claustrum has been the subject of intense research interest in recent years, driven in large part by its extensive connections with various regions of the cerebral cortex and by hypotheses surrounding its possible role in multimodal sensory and/or sensory–emotional integration. Here we employed neuroanatomical tracers to map projections from the claustrum–insular region to the medial prefrontal...
Sensory adaptation is a phenomenon in which neurons are affected not only by their immediate input but also by the sequence of preceding inputs. In visual cortex, for example, neurons shift their preferred orientation after exposure to an oriented stimulus. This adaptation is traditionally attributed to plasticity. We show that a recurrent network generates tuning curve shifts observed in cat and...
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