Search results for: Shuqiu Zhang

Items from 1 to 20 out of 21 results

article

Simultaneous Improvements of Physicochemical Properties and Anti‐Microbial Activity of Berberine via Forming Salt with Gallic Acid

Yi Chen, Xirui Yang, Guolian Ren, Shuqiu Zhang, more

Crystal Research and Technology > 59 > 4 > n/a - n/a

Implementing combination medication through crystal engineering technology receives increasing attention from researchers due to improvements in the clinical treatment effects as well as the physicochemical properties of the drug. Berberine (BER) is commonly used to treat gastroenteritis and bacterial diarrhea, with the problems of poor solubility and low oral bioavailability. Recently, it is found...

article

Solvates of acotiamide hydrochloride: characterization and phase transformation

Guoshun Zhang, Na Wang, Xiaoqing Shang, Lifeng Zhang, more

Acta Crystallographica Section B > 75 > 6 > 1106 - 1114

Five novel crystals of acotiamide hydrochloride (AH) with solvates dimethyl formide (DMF), dimethyl sulfoxide (DMSO), ethyl acetate (EA) and water (W) [1AH‐1W‐1DMF, 1AH‐1DMSO‐I, 1AH‐1DMSO‐II, 1AH‐1W‐1DMSO and 2AH‐2DMSO‐1EA] were characterized using single‐crystal X‐ray diffraction, powder X‐ray diffraction, thermal analysis and Fourier transform infrared spectroscopy. The five crystals can be divided...

article

Design and preparation acid-activated montmorillonite sustained-release drug delivery system for dexibuprofen in vitro and in vivo evaluations

Tingting Li, Lele Zhao, Ziliang Zheng, Min Zhang, more

Applied Clay Science > 2018 > 163 > C > 178-185

Montmorillonite (Mt) plays a very important role in controlling drug delivery. In this paper, the hydrochloric acid (HCl) treated Mt. was exploited to obtain composites, which were able to enhance dexibuprofen (IBU) loading and achieve to sustain release drug. The textural properties of the Mt. were strongly dependent on the treatment of HCl. The drug loading of pristine Mt. was 190 mg/g, while it...

article

Antimalarial activity and metabolism of dihydroartemisinin-derived dimer

Guoshun Zhang, Hualing Dai, Guolian Ren, Xiaoyang Xiao, more

Parasitology Research > 2018 > 117 > 7 > 2243-2254

The dihydroartemisinin-derived dimer (DHA dimer) was synthesized, and its antimalarial activities were evaluated both in vitro and in vivo. The dimer IC₅₀ value of 0.51 ± 0.12 nM in vitro was significantly lower than that of DHA at 1.81 ± 0.70 nM. The dimer ED₅₀ values were 0.44 ± 0.03 and 0.18 ± 0.03 mg/(kg·day) in vivo for intragastric (i.g.) and intravenous (i.v.) groups, respectively, to Plasmodium yoelii...

chapter

Stomata: Biophysical and Biochemical Aspects

William H. Outlaw, Shuqiu Zhang, Daniel R. C. Hite, Anne B. Thistle

Advances in Photosynthesis and Respiration > Photosynthesis and the Environment > 241-259

Summary Regulation of gas exchange by stomata of adjustable aperture size in the leaf epidermis is crucial to a plant’s physiology: sufficient CO₂ must be admitted into the leaves for growth, but loss of water, usually the limiting resource for terrestrial plants, must be minimized. In essence, the study of stomatal movements is an inquiry into accumulation and dissipation of K ...

article

Monitoring and probabilistic risk assessment of chlorothalonil residues in vegetables from Shandong province (China)

Hong Zhang, Yan Nie, Shuqiu Zhang, Wen zheng Wang, more

Regulatory Toxicology and Pharmacology > 2016 > 80 > C > 41-45

The aims of this study were to investigate the contamination status of chlorothalonil pesticide residues in vegetables from Shandong province, and to assess the potential risk of chlorothalonil to consumers based on vegetable consumption and body weight using an improved non-parameter probabilistic model. The results showed that Young children (8 months–6 years old) were more sensitive than General...

article

Risk assessment of pesticide residues in dietary intake of celery in China

Liping Fang, Shuqiu Zhang, Zilei Chen, Hongxia Du, more

Regulatory Toxicology and Pharmacology > 2015 > 73 > 2 > 578-586

Residue risk assessment of pesticides in celery was conducted to provide a scientific basis for agricultural regulation policies and working procedures.Three hundred samples from eight main growing regions in China were collected and pesticide residue analyses were performed using GC–MS/MS and LC-MS/MS methods. Both chronic and acute intake risk of pesticides were assessed. Furthermore, intake risk...

article

A DNA nanomachine based on rolling circle amplification-bridged two-stage exonuclease III-assisted recycling strategy for label-free multi-amplified biosensing of nucleic acid

Qingwang Xue, Yanqin Lv, Hui Cui, Xiaohong Gu, more

Analytica Chimica Acta > 2015 > 856 > Complete > 103-109

An autonomous DNA nanomachine based on rolling circle amplification (RCA)-bridged two-stage exonuclease III (Exo III)-induced recycling amplification (Exo III-RCA-Exo III) was developed for label-free and highly sensitive homogeneous multi-amplified detection of DNA combined with sensitive fluorescence detection technique. According to the configuration, the analysis of DNA is accomplished by recognizing...

article

Two-phase/Three-phase Hollow Fibre Liquid-Phase Simultaneous Microextraction Combined with HPLC for Analysis of Phenolic Acids and Flavonoids in Traditional Chinese Medicine

Shang Li, Shuang Hu, Xuan Chen, Xiaohong Bai, more

Chromatographia > 2015 > 78 > 17-18 > 1159-1167

A two-phase/three-phase hollow fibre liquid-phase simultaneous microextraction (2p/3p-HF-LPSME) method, coupled with high-performance liquid chromatography and ultraviolet detection, was developed and introduced for simultaneous extraction and determination of phenolic acids and flavonoids in Lonicera japonica, Herba Taraxaci and Cortex Eucommiae. Several factors affecting performance were investigated...

article

Ultrasensitive fluorescence detection of nucleic acids using exonuclease III-induced cascade two-stage isothermal amplification-mediated zinc (II)-protoporphyrin IX/G-quadruplex supramolecular fluorescent nanotags

Qingwang Xue, Yanqin Lv, Yuanfu Zhang, Shulin Xu, more

Biosensors and Bioelectronics > 2014 > 61 > Complete > 351-356

A cascadic sensing system was developed for detection of DNA target at ultralow concentration by a combination of magnetic nanoparticles (MNPs) and exonuclease III (Exo III)-induced cascade two-stage isothermal amplification in the study. An ingeniously designed capture hairpin probe (CHP) that integrates target-binding and signal transduction sequences within one multifunctional design was assembled...

article

A convenient sandwich assay of thrombin in biological media using nanoparticle-enhanced fluorescence polarization

Qiaoli Yue, Tongfei Shen, Lei Wang, Shuling Xu, more

Biosensors and Bioelectronics > 2014 > 56 > Complete > 231-236

A new aptamer biosensor was presented for the detection of thrombin in this work, which was based on fluorescence polarization (FP) using silica nanoparticles as enhancement probe. The silica nanoparticles covered by streptavidin were tagged with a thrombin aptamer (5'-biotin-GGTTGGTGTGGTTGG-3'), which was bound to the surface of silica nanoparticle through the specific interaction between streptavidin...

article

A reusable and sensitive biosensor for total mercury in canned fish based on fluorescence polarization

Tongfei Shen, Qiaoli Yue, Xiuxiu Jiang, Lei Wang, more

Talanta > 2013 > 117 > Complete > 81-86

In this work, we developed a sensitive and selective sensor technique for total mercury (Hg) detection in canned fish samples based on the fluorescence polarization (FP) method. The detection principle was that ssDNA containing thymine (T) bases was modified on magnetic nanoparticles (MNPs), which were used as enhancement probe. In the presence of Hg ²⁺ , the ssDNA on MNPs can hybridize with...

article

Synthesis of Fluorescent Gold Nanoclusters Directed by Bovine Serum Albumin and Application for Nitrite Detection

Qiaoli Yue, Lijun Sun, Tongfei Shen, Xiaohong Gu, more

Journal of Fluorescence > 2013 > 23 > 6 > 1313-1318

In the present work, gold nanocluster (GNC) induced by bovine serum albumin (BSA) was synthesized as a novel fluorescence probe to detect nitrite (NO₂ ⁻) sensitively and selectively. The fluorescence of GNC was found to be quenched effectively by NO₂ ⁻. Under the optimum conditions, it was found that the change of fluorescence intensity was proportional with the concentration of NO₂ ⁻ in the linear...

article

Preparation of high solubilizable microemulsion of naproxen and its solubilization mechanism

Qingping Tian, Fude Ren, Zhen Xu, Ying Xie, more

International Journal of Pharmaceutics > 2012 > 426 > 1-2 > 202-210

To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and water were prepared and phase inversion temperature (PIT) method was used to increase drug content. The using of PIT...

article

Localization of NOS-like protein in guard cells of Vicia faba L. and its possible function

Xin Liu, YouQun Wang, WenSuo Jia, ChengHou Lou, more

Chinese Science Bulletin > 2007 > 52 > 1 > 84-90

Using the immuno-fluorescence and immuno-gold electron microscope technology, localization of nitric oxide synthase (NOS)-like proteins was determined in guard cells of Vicia faba L. NOS is mainly localized in nucleus, cytoplasm, chloroplast, mitochondria and the cell wall of guard cells. Scorch and exogenous JA can enhance the level of nitric oxide (NO) and increase NOS activity in both leaf and...

article

Acid catalysed degradation of some spiramycin derivatives found in the antibiotic bitespiramycin

Xiangguo Shi, Shuqiu Zhang, J. Paul Fawcett, Dafang Zhong

Journal of Pharmaceutical and Biomedical Analysis > 2004 > 36 > 3 > 593-600

Bitespiramycin is a novel antibiotic containing a number of 4″-acylated spiramycin derivatives (isovalerylspiramycins I–III, butanoylspiramycin III, propanoylspiramycin III and acetylspiramycin III) as major components. These spiramycin derivatives are susceptible to degradation in acid solution. Liquid chromatography–ion trap mass spectrometry (LC/MS ⁿ ) was used to study the degradation...

article

Protein tyrosine phosphatases involved in signaling of the ABA-induced H₂O₂ generation in guard cells ofVicia faba L.

Wuliang Shi, Wensuo Jia, Xin Liu, Shuqiu Zhang

Chinese Science Bulletin > 2004 > 49 > 17 > 1841-1846

Although protein tyrosine phosphatases (PTPases) play an important role in signal transduction in animal cells, little is known about the function of PTPases in higher plants. Hydrogen peroxide (H₂O₂) and mitogen-activated protein kinases (MAPKs) are the critical components of ABA signaling pathway in guard cells. PTPase is an important regulator of MAPK, which is believed to mediate ABA-induced H...

article

Involvement of Ca²⁺/CaM in the signal transduction of acetylcholine regulating stomatal movement

Hengbin Wang, Shuqiu Zhang, Xuechen Wang, Chenghou Lou

Chinese Science Bulletin > 2003 > 48 > 4 > 351-354

It has been known that the neurotransmitter acetylcholine (ACh) also exists in plants and is able to regulate the movement of stomata. In another aspect, Ca²⁺/CaM as the second messengers have a critical role of signal transduction in stomatal guard-cell. Here we showed that Ca²⁺/CaM were also involved in the ACh regulated stomatal movement. In the medium containing Ca²⁺, the Ca²⁺ channel blockers...

article

Protein tyrosine phosphatase is possibly involved in cellular signal transduction and the regulation of ABA accumulation in response to water deficit inMaize L. coleoptile

Yu Xing, Shuqiu Zhang, Youqun Wang, Wensuo Jia

Chinese Science Bulletin > 2003 > 48 > 5 > 460-465

Water deficit-induced ABA accumulation is an ideal model or “stimulus-response” system to investigate cellular stress signaling in plant cells, using such a model the cellular stress signaling triggered by water deficit was investigated inMaize L. coleoptile. Water deficit-induced ABA accumulation was sensitively blocked by NaVO₃, a potent inhibitor both to plasma membrane H⁺-ATPase (PM-H⁺-ATPase)...

article

Role of acetylcholine on plant root-shoot signal transduction

Hengbin Wang, Shuqiu Zhang, Xuechen Wang, Chenghou Lou

Chinese Science Bulletin > 2003 > 48 > 6 > 570-573

The role of acetylcholine (ACh) on plant rootshoot communication was investigated using the root-split system of Vicia faba L. In the experiments, slight osmotic stress caused the decrease of ACh content in root tips and the xylem sap transported up per time unit from root tip to the shoot when the water potential of the shoot was kept unchanged. It also caused the decrease of ACh content in the abaxial...

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INFONA - science communication portal

Search results for: Shuqiu Zhang

Simultaneous Improvements of Physicochemical Properties and Anti‐Microbial Activity of Berberine via Forming Salt with Gallic Acid

Solvates of acotiamide hydrochloride: characterization and phase transformation

Design and preparation acid-activated montmorillonite sustained-release drug delivery system for dexibuprofen in vitro and in vivo evaluations

Antimalarial activity and metabolism of dihydroartemisinin-derived dimer

Stomata: Biophysical and Biochemical Aspects

Monitoring and probabilistic risk assessment of chlorothalonil residues in vegetables from Shandong province (China)

Risk assessment of pesticide residues in dietary intake of celery in China

A DNA nanomachine based on rolling circle amplification-bridged two-stage exonuclease III-assisted recycling strategy for label-free multi-amplified biosensing of nucleic acid

Two-phase/Three-phase Hollow Fibre Liquid-Phase Simultaneous Microextraction Combined with HPLC for Analysis of Phenolic Acids and Flavonoids in Traditional Chinese Medicine

Ultrasensitive fluorescence detection of nucleic acids using exonuclease III-induced cascade two-stage isothermal amplification-mediated zinc (II)-protoporphyrin IX/G-quadruplex supramolecular fluorescent nanotags

A convenient sandwich assay of thrombin in biological media using nanoparticle-enhanced fluorescence polarization

A reusable and sensitive biosensor for total mercury in canned fish based on fluorescence polarization

Synthesis of Fluorescent Gold Nanoclusters Directed by Bovine Serum Albumin and Application for Nitrite Detection

Preparation of high solubilizable microemulsion of naproxen and its solubilization mechanism

Localization of NOS-like protein in guard cells of Vicia faba L. and its possible function

Acid catalysed degradation of some spiramycin derivatives found in the antibiotic bitespiramycin

Protein tyrosine phosphatases involved in signaling of the ABA-induced H₂O₂ generation in guard cells ofVicia faba L.

Involvement of Ca²⁺/CaM in the signal transduction of acetylcholine regulating stomatal movement

Protein tyrosine phosphatase is possibly involved in cellular signal transduction and the regulation of ABA accumulation in response to water deficit inMaize L. coleoptile

Role of acetylcholine on plant root-shoot signal transduction

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