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Induction of immune tolerance to ox-LDL could reduce atherosclerosis by modulation immune response. We suppose that very low density lipoprotein (VLDL) may have a similar role to ox-LDL in autoimmune response of atherosclerosis. In this study, neonatal rats were injected with ox-LDL, VLDL, or equal-volume saline, respectively. Vaccination with ox-LDL reduced the level of specific antibody, T cells...
Objectives To investigate the possible relationship between circulating oxLDL and oxLDL Ab concentrations in order to better understand the role of oxLDL Ab in atherosclerosis. Design In a cross-sectional study of 86 patients undergoing ultrasonographic scanning of the carotid artery, concentration of circulating oxLDL and oxLDL Ab were determined by ELISA. For multivariate analysis, we also measured...
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