Search results for: Christopher J. Gill

Items from 1 to 16 out of 16 results

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Ear biometrics for patient identification in global health: a field study to test the effectiveness of an image stabilization device in improving identification accuracy

Lauren P. Etter, Elizabeth J. Ragan, Rachael Campion, David Martinez, more

BMC Medical Informatics and Decision Making > 2019 > 19 > 1 > 1-9

Background In many low and middle-income countries (LMICs), difficulties in patient identification are a major obstacle to the delivery of longitudinal care. In absence of unique identifiers, biometrics have emerged as an attractive solution to the identification problem. We developed an mHealth App for subject identification using pattern recognition around ear morphology (Project SEARCH (Scanning...

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“When you are injected, the baby is protected:” Assessing the acceptability of a maternal Tdap vaccine based on mothers’ knowledge, attitudes, and beliefs of pertussis and vaccinations in Lusaka, Zambia

Anna Larson Williams, Lois McCloskey, Magdalene Mwale, Lawrence Mwananyanda, more

Vaccine > 2018 > 36 > 21 > 3048-3053

Severe and fatal pertussis infections are concentrated among infants who are too young to be protected through routine vaccinations. Maternal Tdap (mTdap), which is now the standard of care in the US and UK, is considered to be the most effective way to address this gap in preventative care. Little is known about how pregnant women in low-resource settings might view mTdap. To inform strategies for...

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Diarrhoeal disease trends in the GBD 2015 study: optimism tempered by scepticism

Christopher J Gill, Donald M Thea, Patricia Hibberd

The Lancet Infectious Diseases > 2017 > 17 > 9 > 884-885

article

The Pertussis resurgence: putting together the pieces of the puzzle

Rotem Lapidot, Christopher J. Gill

Tropical Diseases, Travel Medicine and Vaccines > 2016 > 2 > 1 > 1-10

Pertussis incidence is rising in almost every country where acellular pertussis (aP) vaccines have been introduced, and is occurring across all age groups from infancy to adulthood. The key question is why? While several known factors such as waning of immunity, detection bias due to more sensitive tests and higher awareness of the disease among practitioners, and evolutionary shifts among B. pertussis...

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Ear biometrics for patient identification in global health: a cross-sectional study to test the feasibility of a simplified algorithm

Elizabeth J. Ragan, Courtney Johnson, Jacqueline N. Milton, Christopher J. Gill

BMC Research Notes > 2016 > 9 > 1 > 1-12

Background One of the greatest public health challenges in low- and middle-income countries (LMICs) is identifying people over time and space. Recent years have seen an explosion of interest in developing electronic approaches to addressing this problem, with mobile technology at the forefront of these efforts. We investigate the possibility of biometrics as a simple, cost-efficient, and portable...

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Novel Approaches for Visualizing and Analyzing Dose-Timing Data from Electronic Drug Monitors, or “How the ‘Broken Window’ Theory Pertains to ART Adherence”

Christopher J. Gill, Mary Bachman DeSilva, Davidson H. Hamer, Xu Keyi, more

AIDS and Behavior > 2015 > 19 > 11 > 2057-2068

Adherence to antiretroviral medications is usually expressed in terms of the proportion of doses taken. However, the timing of doses taken may also be an important dimension to overall adherence. Little is known about whether patients who mistime doses are also more likely to skip doses. Using data from the completed Adherence for Life randomized controlled trial, we created visual and statistical...

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Antibiotic non-susceptibility among Streptococcus pneumoniae and Haemophilus influenzae isolates identified in African cohorts: a meta-analysis of three decades of published studies

Amy Sarah Ginsburg, Laura Tinkham, Katherine Riley, Noa A. Kay, more

International Journal of Antimicrobial Agents > 2013 > 42 > 6 > 482-491

Management of community-acquired pneumonia caused by Streptococcus pneumoniae and Haemophilus influenzae type B (Hib) can be complicated by emerging antimicrobial non-susceptibility. We conducted a meta-analysis to examine the antibiotic susceptibility of community-acquired invasive infections with S. pneumoniae and Hib in Africa from 1978 to 2011. With the notable exceptions of widespread trimethoprim/sulfamethoxazole...

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Novel assessment of a novel meningitis B vaccine

Christopher J Gill

The Lancet Infectious Diseases > 2013 > 13 > 5 > 381-382

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Systematic review of current and emerging strategies for reducing morbidity from malaria in sickle cell disease

Ehimen C. Aneni, Davidson H. Hamer, Christopher J. Gill

Tropical Medicine & International Health > 18 > 3 > 313 - 327

Sickle cell disease (SCD) is a chronic debilitating disorder affecting erythrocytes, which is especially prevalent throughout Sub‐Saharan Africa and among individuals of African descent. Because malaria is thought to be a significant cause of morbidity and mortality in patients with SCD, malaria chemoprophylaxis is often recommended for these patients. In SCD, malaria chemoprophylaxis reduces malaria...

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Training Zambian traditional birth attendants to reduce neonatal mortality in the Lufwanyama Neonatal Survival Project (LUNESP)

Christopher J. Gill, Nicholas G. Guerina, Charity Mulenga, Anna B. Knapp, more

International Journal of Gynecology and Obstetrics > 2012 > 118 > 1 > 77-82

To provide relevant details on how interventions in the Lufwanyama Neonatal Survival Project (LUNESP) were developed and how Zambian traditional birth attendants (TBAs) were trained to perform them.The study tested 2 interventions: a simplified version of the American Academy of Pediatrics’ neonatal resuscitation protocol (NRP); and antibiotics with facilitated referral (AFR).Key elements that enabled...

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Persistence of the immune response at 5 years of age following infant immunisation with investigational quadrivalent MenACWY conjugate vaccine formulations

Ameneh Khatami, Matthew D. Snape, Elizabeth Davis, Helen Layton, more

Vaccine > 2012 > 30 > 18 > 2831-2838

Serogroup A, C, W-135 and Y meningococcal (MenACWY) conjugate vaccines are recommended for routine adolescent immunisation in the United States and Canada. We evaluated the persistence of bactericidal antibodies through early childhood, following infant immunisation with varying schedules of MenACWY-CRM ₁₉₇ vaccine.UK and Canadian infants were immunised with 2–3 doses of MenACWY-CRM ₁₉₇...

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Importance of Dose Timing to Achieving Undetectable Viral Loads

Christopher J. Gill, Lora L. Sabin, Davidson H. Hamer, Xu Keyi, more

AIDS and Behavior > 2010 > 14 > 4 > 785-793

Little is known about the importance of dose timing to successful antiretroviral therapy (ART). In a cohort comprised of Chinese HIV/AIDS patients, we measured adherence among subjects for 6 months using three methods in parallel: self-report using a visual analog scale (SR-VAS), pill count, and electronic drug monitors (EDM). We calculated two adherence metrics using the EDM data. The first metric...

article

Using Electronic Drug Monitor Feedback to Improve Adherence to Antiretroviral Therapy Among HIV-Positive Patients in China

Lora L. Sabin, Mary Bachman DeSilva, Davidson H. Hamer, Keyi Xu, more

AIDS and Behavior > 2010 > 14 > 3 > 580-589

Effective antiretroviral therapy (ART) requires excellent adherence. Little is known about how to improve ART adherence in many HIV/AIDS-affected countries, including China. We therefore assessed an adherence intervention among HIV-positive patients in southwestern China. Eighty subjects were enrolled and monitored for 6 months. Sixty-eight remaining subjects were randomized to intervention/control...

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Antiretroviral programme in rural Uganda

Christopher J Gill

The Lancet > 2006 > 368 > 9547 > 1556-1557

article

Species-Specific Bacteria Identification Using Differential Mobility Spectrometry and Bioinformatics Pattern Recognition

Marianna Shnayderman, Brian Mansfield, Ping Yip, Heather A. Clark, more

Analytical Chemistry > 2005 > 77 > 18 > 5930 - 5937

article

Foodborne illnesses

Christopher J. Gill, Davidson H. Hamer

Current Treatment Options in Gastroenterology > 2001 > 4 > 1 > 23-38

Opinion statement Foodborne illnesses cause a substantial human and financial burden. Despite sanitary infrastructure improvements, the incidence of foodborne bacterial infections due to non-typhoidal salmonellae (NTS), Campylobacter jejuni, and enterohemorrhagic Escherichia coli (EHEC) has risen over the last two decades. Overall, viruses account for two thirds of all foodborne illness. Most...

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