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Aim
To compare the pharmacokinetics of isoniazid (INH) at doses 5 and 10 mg/kg/day.
Methods
INH concentrations were estimated by high‐performance liquid chromatography in 24 Indian children aged 1 to 15 years on antituberculosis therapy. Blood samples were collected at 0, 2, 4, 6, 8 hours after administration of INH. Patients were randomly given INH at 5 or 10 mg/kg/day and maximum concentrations...
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