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In this study, a three-dimensional mathematical model was used to study the contribution of clathrins during the process of cellular uptake of spherical nanoparticles under different membrane tensions. The clathrin-coated pit (CCP) that forms around the inward budding of the cell membrane was modeled as a vesicle with bending rigidity. An optimization algorithm was proposed for minimizing the total...
Mechanical stimuli play critical roles in cardiovascular diseases, in which in vivo stresses in blood vessels present a great challenge to predict. Based on the structural–thermal coupled finite element method, we propose a thermal expansion method to estimate stresses in multi-layer blood vessels under healthy and pathological conditions. The proposed method provides a relatively simple and convenient...
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