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Polyamines are naturally occurring aliphatic compounds, particularly essential elements for biological functions. These compounds play a central role in regulating molecular pathways which are responsible for cellular proliferation, growth, and differentiation. Importantly, excessive polyamine catabolism can lead to a prominent source of oxidative stress which increases inflammatory response and thought...
The study was carried out to explore the anti-oxidative properties of Eucommia ulmoids flavone. IPEC-J2 cells was cultured in DMEM medium containing 0, 10µg/ml EUF, 0, 40ng/ml LPS and 0 or 10μmol/L LY29400 (PI3K inhibitor) for 2 days. The results reveal that LPS decrease DNA synthesis (P<0.05) and viable number of cells (P<0.05) arrest cell cycle at S-phase and induce apoptosis (P<0.05),...
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