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We studied the formation of mesenchymal islets in the culture of bone marrow cells in vitro. Islet-like structures detected on day 6 of culturing contained a central epithelioid cell (differing from macrophages and fibroblasts) surrounded with round mesenchymal cells. The number of mesenchymal islets increased on days 12-14 of culturing, but decreased to zero by the 24th day. They appeared not only...