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Nanoparticles are small sized (1–100 nm) particles derived from transition metals, silver, copper, aluminum, silicon, carbon and metal oxides that can easily cross the blood–brain barrier (BBB) and/or produce damage to the barrier integrity by altering endothelial cell membrane permeability. However, the influence of nanoparticles on BBB integrity is still not well-known. In this investigation, effect...
Previous reports from our laboratory show that animals treated with engineered nanoparticles derived from metals for 1 week and subjected to hyperthermia showed enhanced neurotoxicity in terms of blood–brain barrier (BBB) disruption, brain edema formation and cell injury. It appears that nanoparticle induced enhanced oxidative stress leads to increased lipid peroxidation and over-production of hydroxyl...
A novel method is proposed for the calibration of channel mismatch in a time-interleaved real-time digital oscilloscope (RTDO). A simple simultaneous equation is derived from the Fourier transform of the time-interleaved signals. Thus, it only requires a transfer function of time-interleaved ADCs (TIADCs), while most of previous works have employed additional filters. A measurement method for the...
With various emerging applications ranging from medicine to materials and electronics, the risk of exposure to nanomaterials is rapidly increasing. Several routes of exposure to nanomaterials exist; the most important being dermal contact and inhalation. In this dermal toxicity study, the cellular effects of carbon-based materials with diameters ranging from micro- to nano-dimension were investigated...
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