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To improve the therapeutic efficacy of herpes simplex virus type 1 (HSV-1) thymidine kinase (tk)/ganciclovir (GCV) therapy, we have made recombinant tk chimeras fused with the arginine-rich (RXP) repeat of herpes simplex virus type 2 (HSV-2) US11 and examined their activity of intercellular trafficking and cytotoxicity. When examined the immunofluorescence staining patterns of RXP/tk fusion proteins...
This paper presents a technique to improve the turning accuracy or to control the cutting errors by in-process measurement. Newly developed “half-line Hartmann test” was applied as an in-process figure measurement for concave mirror cutting experiment. Since the datums of this turning control is in the figure measuring system, machine tool errors and environmental disturbances, primarily, do not influence...
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