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Five patients with rapidly progressive glomerulonephritis (RPGN) that developed during the management of interstitial pneumonitis at our hospital in the past 5 years were studied. In these patients, chronic interstitial pneumonitis preceded the onset of nephritis by periods of 0 to 11 years. All patients had a high titer of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) when RPGN...