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N-Alkaloid acetic acid hydrazides have been obtained by the hydrazinolysis of morpholones, and the acylation reactions of these hydrazides have been carried out. Screening investigations of the synthesized derivatives in vitro and in vivo have revealed, for the first time among the ephedrine alkaloids, a promising compound (N-d-pseudoephedrinylacetic acid hydrazide) possessing pronounced antituberculosis...