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Notch signaling plays an important role in tumor angiogenesis. Recent studies suggest that Notch signaling also regulates the progression of primary melanomas toward an aggressive phenotype. The aim of this study was to investigate the involvement of Notch signaling pathway in organization of tumor cells into capillary-like structures (CLS), the phenomenon also known as vasculogenic mimicry (VM)....
Please cite this paper as: Vartanian, Stepanova, Grigorieva, Solomko, Belkin, Baryshnikov, and Lichinitser (2011). Melanoma Vasculogenic Mimicry Capillary‐Like Structure Formation Depends on Integrin and Calcium Signaling. Microcirculation.18(5), 390–399.
AbstractObjective: We recently demonstrated that the formation of CLSs in vitro, which are thought to be a reconstitution of VM, is controlled...
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