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Abstract. The sequencing of Leishmania major Friedlin chromosome 1 (Chr1), Chr3, and Chr4 has been completed, and several other chromosomes are well underway. The complete genome sequence should be available by 2003. Over 1,000 full-length new genes have been identified, with the majority (~75%) having unknown function. Many of these may be Leishmania (or kinetoplastid) specific. Most interestingly,...