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AbstractRationale: The forced swimming test (FST) is a behavioral test in rodents that predicts the clinical efficacy of many types of antidepressant treatments. Recently, a behavior sampling technique was developed that scores individual response categories, including swimming, climbing and immobility. Although all antidepressant drugs reduce immobility in the FST, at least two distinct active behavioral...
Failure caused by poor performance renders a system just as useless as failure caused by functional errors, and can be even more expensive to correct. For many years, performance in software systems has been achieved through a ‘fix-it-later’ approach, using optimisation and tuning techniques. Recent evidence shows that, with the increased use of highly complex, multi-layered, client/server, distributed...
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