Search results for: J. Fürst

Items from 1 to 20 out of 52 results

article

Use of eDNA and conventional sampling methods to survey rock pool (gnamma) biodiversity on granite inselbergs

Damian R. Michael, Allan Murray, Phil Murray, Beau Murray, more

Sampling of environmental DNA (eDNA) and high‐throughput sequencing is emerging as an effective biodiversity assessment method in aquatic systems and may have utility for biodiversity inventory in terrestrial environments. Rock pools (gnammas) on granite inselbergs support a rich community of aquatic organisms and are culturally important to Indigenous peoples worldwide. However, the application of...

article

A One‐Pot, Whole‐Cell Biocatalysis Approach for Vanillin Production using Lignin Oil

Ivana Marić, Yiming Guo, Maximilian J. L. J. Fürst, Korneel Van Aelst, more

Advanced Synthesis & Catalysis > 365 > 22 > 3987 - 3995

Vanillin is a popular and versatile flavor compound, almost entirely produced from petroleum‐derived phenol by a multi‐step chemical synthesis. The process is hazardous to the environment and unsustainable for its fossil oil usage. Therefore, developing environmentally friendly, efficient, and sustainable routes to biobased vanillin is essential. Here, we report on vanillin production from 4‐n‐propylguaiacol...

article

Losing a parent to cancer as a teenager: Family cohesion in childhood, teenage, and young adulthood as perceived by bereaved and non‐bereaved youths

Dröfn Birgisdóttir, Tove Bylund Grenklo, Tommy Nyberg, Ulrika Kreicbergs, more

Psycho‐Oncology > 28 > 9 > 1845 - 1853

Objective The aim of this study was to investigate levels of perceived family cohesion during childhood, teenage years, and young adulthood in cancer‐bereaved youths compared with non‐bereaved peers. Methods In this nationwide, population‐based study, 622 (73%) young adults (aged 18‐26) who had lost a parent to cancer 6 to 9 years previously, when they were teenagers (aged 13–16), and 330 (78%)...

article

Stabilization of cyclohexanone monooxygenase by computational and experimental library design

Maximilian J. L. J. Fürst, Marjon Boonstra, Selle Bandstra, Marco W. Fraaije

Biotechnology and Bioengineering > 116 > 9 > 2167 - 2177

Enzymes often by far exceed the activity, selectivity, and sustainability achieved with chemical catalysts. One of the main reasons for the lack of biocatalysis in the chemical industry is the poor stability exhibited by many enzymes when exposed to process conditions. This dilemma is exemplified in the usually very temperature‐sensitive enzymes catalyzing the Baeyer–Villiger reaction, which display...

article

Exploring the Biocatalytic Potential of a Self‐Sufficient Cytochrome P450 from Thermothelomyces thermophila

Maximilian J. L. J. Fürst, Bianca Kerschbaumer, Claudia Rinnofner, Anna K. Migglautsch, more

Advanced Synthesis & Catalysis > 361 > 11 > 2487 - 2496

Among nature's arsenal of oxidative enzymes, cytochrome P450s (CYPs) catalyze the most challenging reactions, the hydroxylations of non‐activated C−H bonds. Human CYPs are studied in drug development due to their physiological role at the forefront of metabolic detoxification, but their challenging handling makes them unsuitable for application. CYPs have a great potential for biocatalysis, but often...

article

Direct analysis of textile dyes from trace fibers by automated microfluidics extraction system coupled with Q-TOF mass spectrometer for forensic applications

Nadia Sultana, Sean Gunning, Stephen J. Furst, Kenneth P. Garrard, more

Forensic Science International > 2018 > 289 > C > 67-74

Textile fiber is a common form of transferable trace evidence at the crime scene. Different techniques such as microscopy or spectroscopy are currently being used for trace fiber analysis. Dye characterization in trace fiber adds an important molecular specificity during the analysis. In this study, we performed a direct trace fiber analysis method via dye characterization by a novel automated microfluidics...

article

Systemic Solutions, Legislative And Organizational Frameworks Aimed To Prevent Or Mitigate Drug Shortages In European Countries

T Bochenek, BB Godman, A Bucsics, E De Weerdt, more

Value in Health > 2016 > 19 > 7 > A445

chapter

Further Characterization of the Nematode IClnN2 Protein Reconstituted in Lipid Bilayers

M. Ritter, C. Bertocchi, M. Jakab, J. Fürst, more

Advances in Experimental Medicine and Biology > Cell Volume and Signaling > Cell Volume, Cytoskeleton and Apoptosis > 245-251

4. Conclusions The results presented in this study confirm previous findings demonstrating voltage-dependent inactivation of the nematode ICln splice variant IClnN2. Furthermore they demonstrate that antibodies directed against the additional 20 amino acids encoded by exon 2a are able to suppress the inactivation of IClnN2, thus mimicking the action of the ICln operon partner protein Nx on reconstituted...

chapter

Numerical solution of several 2D and 3D internal flow problems

M. Fialová, J. Fořt, J. Fürst, M. Huněk, more

Lecture Notes in Physics > Fifteenth International Conference on Numerical Methods in Fluid Dynamics > 364-369

The work deals with numerical solution of 3D Euler and 2D or 3D Navier-Stokes equations. Incompressible, subsonic and transonic flow through a cascade or in a channel of constant cross-section is numerically solved. Two versions of Lax-Wendroff type finite volume schemes and Runge-Kutta scheme were developed for 3D computations. The work presents some 2D and 3D results of laminar viscous flows through...

chapter

Probing of the ICln Channel Pore by Cysteine Mutagenesis and Cadmium-Block

M. Jakab, M. L. Garavaglia, J. Fürst, S. Rodighiero, more

Advances in Experimental Medicine and Biology > Cell Volume and Signaling > Ion Channels and Exchangers > 99-108

4. Conclusions Purified, water-soluble ICln protein forms ion channels by spontaneously incorporating into artificial lipid bilayers. Site-directed mutation experiments revealed E41 and D49 as the amino acids responsible for the Ca²⁺-dependence of the channels’ ion selectivity and G49 to be part of the putative nucleotide binding site of the protein. H64 could be pinpointed within the ion conducting...

chapter

FVM-FEM Coupling and its Application to Turbomachinery

J. Fořt, J. Fürst, J. Halama, K. Kozel, more

Springer Proceedings in Mathematics > Finite Volumes for Complex Applications VI Problems & Perspectives > Regular papers > 505-512

The paper deals with the numerical solution of turbulent flows through a 2D turbine cascade considering heat exchange between the gas and the solid blade. The flow field is described by the Favre averaged Navier-Stokes equations, and the temperature field inside the solid blade is given by the Laplace equation. Both parts are coupled in order to achieve continuity of the temperature as well as of...

chapter

Numerical Simulation of the Stratified Flow Past a Body

L. Beneš, J. Fürst

Numerical Mathematics and Advanced Applications 2009 > Contributed Papers > 155-162

The article deals with the numerical simulation of 2D and 3D unsteady incompressible stratified flows. Initial system of equations is the Boussinesq approximation of the Navier–Stokes equations. The flow field in the towing tank with a moving sphere is modeled for a wide range of Richardson numbers. The obstacle is modeled via penalization technique. The resulting set of partial differential equations...

chapter

Numerical Simulation of the Towing Tank Problem Using High Order Schemes

L. Beneš, J. Fürst, Ph. Fraunié

Lecture Notes in Computational Science and Engineering > BAIL 2008 - Boundary and Interior Layers > Contributed papers > 79-93

The article deals with the numerical simulation of 2D and 3D unsteady incompressible flows with stratifications. The mathematical model is based on the Boussinesq approximation of the Navier-Stokes equations. The flow field in the towing tank with a moving sphere is modelled for a wide range of Richardson numbers. The obstacle is modeled via appropriate source terms. The resulting set of partial differential...

article

Unresolved grief and its consequences. A nationwide follow-up of teenage loss of a parent to cancer 6–9 years earlier

T. Bylund-Grenklo, C. J. Fürst, T. Nyberg, G. Steineck, more

Supportive Care in Cancer > 2016 > 24 > 7 > 3095-3103

Purpose The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. Methods In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief and...

article

The impact of depression on Veterans with PTSD and traumatic brain injury: A diffusion tensor imaging study

Linda Isaac, Keith L. Main, Salil Soman, Ian H. Gotlib, more

Biological Psychology > 2015 > 105 > Complete > 20-28

A significant proportion of military personnel deployed in support of Operation Enduring Freedom and Operation Iraqi Freedom were exposed to war-zone events associated with traumatic brain injury (TBI), depression (DEP) and posttraumatic stress disorder (PTSD). The co-occurrence of TBI, PTSD and DEP in returning Veterans has recently increased research and clinical interest. This study tested the...

chapter

A study of regenerative energy systems and PUMP applications in distributed DC-microgrids

S. Oberlander-Horath, P. Lohdefink, M. Grillenberger, J. Furst, more

2014 6th European Embedded Design in Education and Research Conference (EDERC) > 137 - 141

2014 6th European Embedded Design in Education and Research Conference (EDERC)

The concept of distributed energy generation in DC-microgrids is becoming more and more popular, due to the enhanced advantages of energy self-supply and minimizing of conversion losses. Based on a sewage application containing a photovoltaic system and a pump application, this paper describes the individual subsystems of a DC-microgrid. A Matlab/Simulink simulation will be presented to view the behaviour...

article

Effect of oral nutritional supplementation on wound healing in diabetic foot ulcers: a prospective randomized controlled trial

D. G. Armstrong, J. R. Hanft, V. R. Driver, A. P. S. Smith, more

Diabetic Medicine > 31 > 9 > 1069 - 1077

AimsAmong people with diabetes, 10–25% will experience a foot ulcer. Research has shown that supplementation with arginine, glutamine and β‐hydroxy‐β‐methylbutyrate may improve wound repair. This study tested whether such supplementation would improve healing of foot ulcers in persons with diabetes. MethodsAlong with standard of care, 270 subjects received, in a double‐blinded fashion, (twice per...

article

IMPACTS OF LAND COVER CHANGE SCENARIOS ON STORM RUNOFF GENERATION: A BASIS FOR MANAGEMENT OF THE NYANDO BASIN, KENYA

L. O. Olang, P. M. Kundu, G. Ouma, J. Fürst

Land Degradation & Development > 25 > 3 > 267 - 277

The effects of conceptual land cover change scenarios on the generation of storm runoffs were evaluated in the Nyando Basin. The spatial scenarios represented alternatives that vary between full deforestation and reforestation. Synthetic storm events of depths 40, 60 and 80 mm were formulated according to the rainfall patterns and assumed to have durations corresponding to the runoff times of concentration...

article

PP083—Dabigatran– demonstrates the need for comprehensive approaches to optimise the use of new drugs

R.E. Malmstrom, B. Godman, E. Diogene, M. Bennie, more

Clinical Therapeutics > 2013 > 35 > 8(S) > e43-e44

chapter

Complex polarization in non z-cut whispering gallery mode resonators

F. Sedlmeir, M. Hauer, J. Furst, D. V. Strekalov, more

2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC > 1

2013 Conference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference CLEO EUROPE/IQEC

Birefringent crystals like lithium niobate show a very strong χ⁽²⁾ non-linear response and have thus been used in a whispering galley mode (WGM) supporting geometry to achieve extremely high conversion efficiencies[1,2]. In a uniaxial crystal, light is split into two different eigenpolarizations showing different phase velocities. Usually the WGM resonators are fabricated such that the optic axis...

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INFONA - science communication portal

Search results for: J. Fürst

Use of eDNA and conventional sampling methods to survey rock pool (gnamma) biodiversity on granite inselbergs

A One‐Pot, Whole‐Cell Biocatalysis Approach for Vanillin Production using Lignin Oil

Losing a parent to cancer as a teenager: Family cohesion in childhood, teenage, and young adulthood as perceived by bereaved and non‐bereaved youths

Stabilization of cyclohexanone monooxygenase by computational and experimental library design

Exploring the Biocatalytic Potential of a Self‐Sufficient Cytochrome P450 from Thermothelomyces thermophila

Direct analysis of textile dyes from trace fibers by automated microfluidics extraction system coupled with Q-TOF mass spectrometer for forensic applications

Systemic Solutions, Legislative And Organizational Frameworks Aimed To Prevent Or Mitigate Drug Shortages In European Countries

Further Characterization of the Nematode IClnN2 Protein Reconstituted in Lipid Bilayers

Numerical solution of several 2D and 3D internal flow problems

Probing of the ICln Channel Pore by Cysteine Mutagenesis and Cadmium-Block

FVM-FEM Coupling and its Application to Turbomachinery

Numerical Simulation of the Stratified Flow Past a Body

Numerical Simulation of the Towing Tank Problem Using High Order Schemes

Unresolved grief and its consequences. A nationwide follow-up of teenage loss of a parent to cancer 6–9 years earlier

The impact of depression on Veterans with PTSD and traumatic brain injury: A diffusion tensor imaging study

A study of regenerative energy systems and PUMP applications in distributed DC-microgrids

Effect of oral nutritional supplementation on wound healing in diabetic foot ulcers: a prospective randomized controlled trial

IMPACTS OF LAND COVER CHANGE SCENARIOS ON STORM RUNOFF GENERATION: A BASIS FOR MANAGEMENT OF THE NYANDO BASIN, KENYA

PP083—Dabigatran– demonstrates the need for comprehensive approaches to optimise the use of new drugs

Complex polarization in non z-cut whispering gallery mode resonators

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