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The aim of the present work was to study the nephrotoxicity of aluminum lactate administered for 3 months (0.57mg/100g bodyweight aluminum, i.p., three times per week) to male Wistar rats. Renal function was studied after 6 weeks of treatment (urine was obtained from rats in metabolic cages) and at the end of the treatment using clearance techniques. Another group of rats was used as kidneys donors...
AbstractThe present study was undertaken to investigate if the source of oxidative stress and the renal injury produced by mercuric chloride could be renal ischaemia. Verapamil Vp was used because it was described that calcium channel blockers protect cells from nephrotoxicants and from ischaemia. Vp (75g/kg, i.v.; 30min before HgCl2 injection) prevented mercuric chloride renal injury observed 1h...
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