Search results for: May-Yung Yen

Items from 1 to 20 out of 24 results

article

Ambient Air Pollution and the Risk of Central Retinal Artery Occlusion

Hui-Chen Cheng, Ren-Hao Pan, Huan-Jui Yeh, K. Robert Lai, more

Ophthalmology > 2016 > 123 > 12 > 2603-2609

To investigate whether daily changes in ambient air pollution were associated with an increased risk of central retinal artery occlusion (CRAO).Retrospective population-based cohort study.We identified patients newly diagnosed with CRAO between 2001 and 2013 in a representative database of 1 000 000 patients that were randomly selected from all registered beneficiaries of the National Health Insurance...

article

A Nationwide Study

Hui-Chen Cheng, Huan-Jui Yeh, Nicole Huang, Yiing-Jenq Chou, more

Ophthalmology > 2015 > 122 > 12 > 2553-2559

To investigate whether amiodarone use is associated with an increased risk of optic neuropathy.Retrospective population-based cohort study.Patients newly treated with amiodarone between 2005 and 2009 were identified from the Taiwan National Health Insurance Research Database. For each case patient, the study also included 4 age- and gender-matched control subjects who did not receive amiodarone treatment...

article

Neuroimaging and clinical features of patients with optic nerve hypoplasia in Taiwan

Hui-Chen Cheng, May-Yung Yen, An-Guor Wang

Taiwan Journal of Ophthalmology > 2015 > 5 > 1 > 15-18

To investigate the clinical and neuroradiographic features of Chinese patients with optic nerve hypoplasia (ONH).This was a retrospective case series study. The medical records and magnetic resonance imaging (MRI) studies of patients diagnosed with ONH from September 2001 to December 2013 in the neuro-ophthalmology clinic of Taipei Veterans General Hospital were reviewed.A total of eight eyes of five...

article

Leber's hereditary optic neuropathy masquerading as optic neuritis with spontaneous visual recovery

Tsui‐Kang Hsu, An‐Guor Wang, May‐Yung Yen, Jorn‐Hon Liu

Clinical and Experimental Optometry > 97 > 1 > 84 - 86

We report a case of Leber's hereditary optic neuropathy (LHON) masquerading as optic neuritis with late visual recovery. A 28‐year‐old man had gradual visual loss in both eyes for two weeks. Visual acuity was 0.4 in the right eye and 0.7 in the left. Fundus examination revealed hyperaemic discs in each eye. Fluorescein angiography revealed dye leakage at both optic discs in the late phase. Static...

article

Foville's syndrome with ipsilateral internuclear ophthalmoplegia due to spontaneous pontine hemorrhage

Hui-Chen Cheng, May-Yung Yen, An-Guor Wang

Taiwan Journal of Ophthalmology > 2013 > 3 > 2 > 75-77

A 30-year-old male presented to the emergency department with a complaint of acute headache with pain in the right eye and simultaneous weakness and numbness on his left side. Results of ophthalmic examinations showed limited abduction and adduction only in the right eye, while the vertical movement was normal. Mild ptosis with concurrent miosis oculus dexter was also found. A neurological examination...

article

Reply from the authors

Shih-Yun Lee, An-Guor Wang, May-Yung Yen

Taiwan Journal of Ophthalmology > 2012 > 2 > 3 > 114

article

Chiasmal optic neuritis: A report of three cases

Shih-Yun Lee, An-Guor Wang, May-Yung Yen

Taiwan Journal of Ophthalmology > 2012 > 2 > 2 > 68-72

Chiasmal optic neuritis (ON), a rare condition that affects the optic chiasm, is mostly associated with inflammatory demyelinating disorders and may be the initial manifestation of multiple sclerosis (MS). Here, we reported three cases of MS with chiasmal optic neuritis. The clinical manifestations, neuroimaging results, and visual prognosis were evaluated in each patient. Routine eye examinations...

article

Idiopathic intracranial hypertension: Clinical features in Chinese patients

I-Hsien Liu, An-Guor Wang, May-Yung Yen

Japanese Journal of Ophthalmology > 2011 > 55 > 2 > 138-142

Purpose To describe the clinical features and visual outcomes of idiopathic intracranial hypertension (IIH) in Chinese patients. Methods We retrospectively reviewed the charts of patients diagnosed with IIH in Taipei Veterans General Hospital from 1981 to 2009. Demographic data, clinical features, laboratory data, treatment, and visual outcomes were analyzed. Results Twelve patients were included,...

article

“Seeing but not identifying”: pure alexia coincident with prosopagnosia in occipital arteriovenous malformation

Yu-Chi Liu, An-Guor Wang, May-Yung Yen

Graefe's Archive for Clinical and Experimental Ophthalmology > 2011 > 249 > 7 > 1087-1089

Background Pure alexia and prosopagnosia are two separate and uncommon disorders of visual recognition in neuro-ophthalmology. We report an extremely rare case of pure alexia coincident with prosopagnosia secondary to occipital arteriovenous malformation. The manifestations of these two visual recognition disorders are also described. Methods A 35-year-old, left-handed women had suffered from severe...

article

Reply

May‐Yung Yen

Acta Ophthalmologica > 88 > 4 > e127 - e127

article

Novel Mutations of the OPA1 Gene in Chinese Dominant Optic Atrophy

May-Yung Yen, An-Guor Wang, Yen-Ching Lin, Ming-Ji Fann, more

Ophthalmology > 2010 > 117 > 2 > 392-396.e1

To investigate OPA1 gene mutations in Chinese patients with autosomal dominant optic atrophy and sporadic optic atrophy.Molecular genetic studies and observational case series.Twenty-four patients from 10 unrelated Chinese pedigrees of autosomal-dominant optic atrophy, 35 isolated cases with bilateral optic atrophy of unknown cause, and 50 unrelated normal controls.Genomic DNA was extracted from peripheral...

article

Orbital arteriovenous malformation

Tsung-Yu Ho, An-Guor Wang, Moo-Chiou Lin, May-Yung Yen

Japanese Journal of Ophthalmology > 2010 > 54 > 6 > 636-637

article

OPA1 expression in the human retina and optic nerve

An-Guor Wang, Ming-Ji Fann, Hsin-Yi Yu, May-Yung Yen

Experimental Eye Research > 2006 > 83 > 5 > 1171-1178

Mutations in the optic atrophy type 1 (OPA1) gene give rise to human autosomal dominant optic atrophy. The purpose of this study is to investigate OPA1 protein expression in the human retina and optic nerve. A rabbit polyclonal antiserum was generated using a fusion protein covering amino acids 647 to 808 of the human OPA1 protein as the immunogenic antigen. Western blot and immunofluorescence staining...

article

Early Relapse in Multiple Sclerosis-Associated Optic Neuritis Following the Use of Interferon b-1a in Chinese Patients

An-Guor Wang, Yen-Ching Lin, Shuu-Jiun Wang, Ching-Piao Tsai, more

Japanese Journal of Ophthalmology > 2006 > 50 > 6 > 537-542

Purpose The incidence of multiple sclerosis (MS) is relatively rare in Chinese. The beneficial effect of interferon β-1a in modifying the disease course of MS has been rarely analyzed in Chinese patients. The aim of this study was to investigate the clinical response to interferon β1-a in Chinese patients with MS-associated optic neuritis (ON). Methods A retrospective case control study was conducted...

article

Leber's hereditary optic neuropathy: A multifactorial disease

May-Yung Yen, An-Guor Wang, Yau-Huei Wei

Progress in Retinal and Eye Research > 2006 > 25 > 4 > 381-396

Leber's hereditary optic neuropathy (LHON) is a maternally transmitted disease characterized by acute or subacute visual loss predominantly affecting young men. The majority of LHON cases are caused by one of the three primary mitochondrial DNA (mtDNA) mutations: G3460A/ND1, G11778A/ND4, or T14484C/ND6. Although the primary etiological factor of LHON is a mtDNA mutation, the presence of a primary...

article

A Case of Branch Retinal Artery Occlusion Associated with Presumed Optic Neuritis

Chun-Pin Tsai, May-Yung Yen, Wen-Ming Hsu, An-Guor Wang

Japanese Journal of Ophthalmology > 2006 > 50 > 4 > 393-394

article

Low Conversion Rate to Multiple Sclerosis in Idiopathic Optic Neuritis Patients in Taiwan

Yen-Ching Lin, May-Yung Yen, Wen-Ming Hsu, Hui-Chen Lee, more

Japanese Journal of Ophthalmology > 2006 > 50 > 2 > 170-175

Purpose To investigate the clinical characteristics of patients with idiopathic optic neuritis (ON) in Taiwan and to assess the conversion rate to multiple sclerosis (MS) in these patients. Methods We studied the medical records of a total of 109 patients with a clinical diagnosis of idiopathic ON treated in the Taipei Veterans General Hospital during the period from January 1986 to May 2003. Clinical...

article

Acute comitant strabismus after chalazion incision

Tung-Mei Kuang, May-Yung Yen, An-Guor Wang, Wen-Ming Hsu

Annals of Ophthalmology > 2004 > 36 > 1 > 50-52

Acute acquired comitant esotropia rarely occurs in older children and adults. Short-term occlusion of one eye, illness or emotional stress can decompensate the underlying heterophoria. We report a case of a 6-year-old child who developed 35 prism dioptors of acute esotropia after one-day occlusion of one eye for chalazion incision. Motility analysis to rule out paretic deviation is imminent. Waiting...

article

Change of gene expression profiles in the retina following optic nerve injury

An-Guor Wang, Chu-Hsuan Chen, Chu-Wen Yang, May-Yung Yen, more

Molecular Brain Research > 2002 > 101 > 1-2 > 82-92

The purpose of the present study was to search for changes in gene expression patterns in the retina following optic nerve injury. We conducted a subtractive hybridization for comparison of the mRNAs in those retinas receiving optic nerve crush injury and those receiving sham operation. Both forward and reverse subtractions were carried out for 8-h and 24-h time points postoperatively. Resultant subtractive...

article

Leber's Hereditary Optic Neuropathy-The Spectrum of Mitochondrial DNA Mutations in Chinese Patients

May-Yung Yen, An-Guor Wang, Wei-Ling Chang, Wen-Ming Hsu, more

Japanese Journal of Ophthalmology > 2002 > 46 > 1 > 45-51

Purpose: To investigate the spectrum of mitochondrial DNA (mtDNA) mutations in Chinese patients with Leber's hereditary optic neuropathy (LHON), optic atrophy of unknown etiology, and optic neuropathy of known etiology.Methods: Twenty-seven patients from 25 LHON pedigrees, 22 patients with bilateral optic atrophy of unknown etiology, 21 patients with optic neuropathy of known etiology, and 25 normal...

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INFONA - science communication portal

Search results for: May-Yung Yen

Ambient Air Pollution and the Risk of Central Retinal Artery Occlusion

A Nationwide Study

Neuroimaging and clinical features of patients with optic nerve hypoplasia in Taiwan

Leber's hereditary optic neuropathy masquerading as optic neuritis with spontaneous visual recovery

Foville's syndrome with ipsilateral internuclear ophthalmoplegia due to spontaneous pontine hemorrhage

Reply from the authors

Chiasmal optic neuritis: A report of three cases

Idiopathic intracranial hypertension: Clinical features in Chinese patients

“Seeing but not identifying”: pure alexia coincident with prosopagnosia in occipital arteriovenous malformation

Reply

Novel Mutations of the OPA1 Gene in Chinese Dominant Optic Atrophy

Orbital arteriovenous malformation

OPA1 expression in the human retina and optic nerve

Early Relapse in Multiple Sclerosis-Associated Optic Neuritis Following the Use of Interferon b-1a in Chinese Patients

Leber's hereditary optic neuropathy: A multifactorial disease

A Case of Branch Retinal Artery Occlusion Associated with Presumed Optic Neuritis

Low Conversion Rate to Multiple Sclerosis in Idiopathic Optic Neuritis Patients in Taiwan

Acute comitant strabismus after chalazion incision

Change of gene expression profiles in the retina following optic nerve injury

Leber's Hereditary Optic Neuropathy-The Spectrum of Mitochondrial DNA Mutations in Chinese Patients

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