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AbstractObjective: A single oral dose of paracetamol (20mgkg1) was given to 38 Chinese patients with non-insulin-dependent diabetes mellitus (NIDDM) who had either normal renal function or varying degrees of renal impairment, with creatinine clearances ranging from 4 to 123mlmin11.73m2. The plasma and urinary concentrations of paracetamol and its major metabolites were measured by high-performance...