The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Non-Alcohol Liver Disease (NAFLD) is nowadays the most common liver disease in Western Countries. It is the chronic condition of fat expansion in liver, which is not associated with alcohol consumption. Quantitating steatosis in liver biopsies could provide objective measurement of the severity of the disease, instead of using semi-quantitative scoring systems. The current work, introduces an automated...
Quantitative ultrasound has been used to evaluate bone fracture healing for over five decades. Animal and clinical studies have showed that the propagation velocity and attenuation are significantly different between fresh fractures, bone unions, and delayed unions or non-unions. Follow-up measurements have also indicated that the velocity typically increases during healing which makes feasible to...
The bone healing process involves a sequence of cellular action and interaction, regulated by biochemical and mechanical signals. Experimental studies have shown that ultrasound accelerates bone solidification and enhances the underlying healing mechanisms. An integrated computational model is presented for deriving predictions of bone healing under the presence of ultrasound.
The bone healing process involves a sequence of cellular actions and interactions, regulated by biochemical and mechanical signals. Experimental studies have shown that ultrasound accelerates bone solidification and enhances the underlying healing mechanisms. We present a mathematical model for deriving predictions of bone healing under the presence of ultrasound. The model consists of i) partial...
The dipolar gradient theory of elasticity has been recently very attractive for the ultrasonic characterization of bone since it includes intrinsic parameters that combine microstructural effects with the macrostructural behavior. Nevertheless this is the special case of Mindlin's Form-II strain gradient elastic theory, which includes two intrinsic parameters i.e., one for micro-stiffness and one...
In the process of fracture healing, several phases of recovery are observed as the mechanical stability, continuity and normal load carrying capacity are gradually restored. The ultrasonic monitoring and discrimination of different healing stages is a complex process due to the significant microstructure and porous nature of osseous and callus tissues. In this study, we investigate the influence of...
The quantitative determination of wave dispersion and attenuation in bone is an open research area as the factors responsible for ultrasound absorption and scattering in composite biological tissues have not been completely explained. In this study, we use the iterative effective medium approximation (IEMA) proposed in [1] so as to calculate phase velocity and attenuation in media with properties...
Bone healing involves a series of complicated cellular and molecular mechanisms that result in bone formation. Several mechanobiological models have been developed to simulate these cellular mechanisms via diffusive processes. In most cases solution to diffusion equations is accomplished using the Finite Element Method (FEM) which however requires global remeshing in problems with moving or new born...
Ultrasonic evaluation of bone fracture healing has been recognized as an important assessment method which reflects material, mechanical and structural properties. The objective of the present study is to examine the monitoring role of quantitative ultrasound by conducting axial transmission measurements of the propagation velocity of the first arriving signal (FAS) for two dimensional numerical models...
The linear theory of classical elasticity cannot effectively describe bone's mechanical behavior since only homogeneous media and local stresses are assumed. Additionally, it cannot predict the dispersive nature of Rayleigh wave which has been experimental observed. By adopting Mindlin Form II gradient elastic theory and performing Boundary Element (BEM) simulations we also recently demonstrated Rayleigh...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.