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Background Replication timing experiments that use label incorporation and high throughput sequencing produce peaked data similar to ChIP-Seq experiments. However, the differences in experimental design, coverage density, and possible results make traditional ChIP-Seq analysis methods inappropriate for use with replication timing. Results To accurately detect and classify regions of replication...
Assigning global unique persistent identifiers (GUPIs) to datasets has the goal of improving their accessibility and simplifying how they are referenced and reused. However, as repositories receive more and complex data, attesting for the identity of datasets attached to persistent identifiers over time is becoming more challenging. This is due to the nature of scientific research data, which is generated...
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