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Background Gold nanorods (GNRs) display unique capacity to absorb and scatter near infrared light, which arises from their peculiar composition of surface plasmon resonances. For this reason, GNRs have become an innovative material of great hope in nanomedicine, in particular for imaging and therapy of cancer, as well as in photonic sensing of biological agents and toxic compounds for e.g. biomedical...
Keratoconus is an ophthalmic disease in which the cornea acquires an abnormal conical shape that prevents the correct focusing on the retina, causing visual impairment. The late diagnosis of keratoconus is among the principal causes of corneal transplantation surgery. In several previous studies, a different organization sutural lamellae was observed in keratoconic corneas compared to healthy corneas...
Gold nanorods (GNRs) coated with silica shells, modified with polyethylene glycol (PEG) and finally functionalized with cell penetrating peptides (CPPs) are tested in cellular uptake and cell viability. Different silica shell thicknesses (5 and 30 nm) were chosen and samples were characterized both morphologically by TEM and DLS and optically by spectrophotometry. A murine macrophagic cellular line...
Due to their tunable surface plasmon and functional photothermal effects, gold nanorods (GNRs) have proved to be promising in a wide range of biomedical applications such as imaging, hyperthermia therapy and drug delivery. All these applications can be controlled by the use of near infrared (NIR) light, which can penetrate deep into human tissues with minimal invasiveness. AuNRs thus hold the potential...
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