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In this paper, we present a study of real-time adsorption on thin film Molecularly imprited polymer (MIP) coating based on commercial nucleotides Adenosine Mono Phosphate (AMP). The MIP sensitive layer is deposited on top of the propagation path of a Love wave sensor. Detection tests of different concentrations of AMP have been performed in aqueous media through a microfluidic chip placed above the...
Love wave sensor combined with molecularly imprinted polymer (MIP) is introduced. The overall aim of this work is to develop and validate a quantitative, non-invasive diagnosis tool to specific detection of colon cancer biomarkers. This work exhibits the validation of a MIP thin film's coating process, allowing high sensitivity of the resulting sensor. Morphology and print effect of the MIP film (sensitive...
In this paper, we present a process for thin film MIP coating based on commercial nucleotides Adenosine Mono Phosphate (AMP). The compatibility of the MIP film with acoustic propagation and the sensor sensitivity for the rebinding of AMP has been verified. Thin and porous layers of AMP-based MIP layers were successfully deposited on the sensor surface. Detection tests of AMP have been performed in...
The overall objective of this work is to develop and to validate a quantitative, non-invasive diagnosis tool to monitor the efficiency of colorectal cancer chemotherapy. This paper deals with the validation of a molecularly imprinted polymer (MIP) thin film's coating process, allowing high sensitivity of the resulting microsensor. After description of the Love wave sensor and of the MIP coating process,...
The overall objective of this work is to develop and validate a quantitative, non-invasive therapeutic tool to detect selected urinary modified nucleosides as biomarkers of colorectal cancer chemotherapy and to monitor in fine the efficiency of the chemotherapy. Our methodology takes the advantage of high sensitivity of acoustic biosensor combined with high selectivity and robustness of thin molecularly...
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