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Nanoparticles with diameter and refractive index similar to viruses were detected by using a local evanescent array coupled biosensor with an integrated photodetector array on a CMOS chip.
Mycobacterium tuberculosis has two discrete β-ketoacyl synthases encoded by kasA and kasB that are located in tandem within a five-gene operon that has been implicated in isoniazid-sensitivity and mycolic acid synthesis. We have developed an in vitro meromycolic acid synthase assay to elucidate the anabolic role of these enzymes. Overproduction of KasA and KasB individually and together in M. smegmatis...
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