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This paper presents recent results from our continued development of a 0.5 T whole-body MRI magnet at the Francis Bitter Magnet Laboratory. HyperTech Research Corp. (Columbus, OH) manufactures the conductor for this project. During the past year, we have found that our technique, originally developed successfully to splice unreacted multifilament wires, works much better,...
In this paper, we present a new magnetophoretic cell separation method based on the magnetic susceptibility differences between cells and medium. Since the dimension of cells is only a few dozen micrometers, it is difficult to discriminate cells only by low magnetic force acting on biological cells. To improve the efficiency of this label-free magnetophoretic separation, the magnetic susceptibility...
Detection of lymph node (LN) metastasis by magnetic resonance imaging (MRI) has obtained clinical significance for treating cancer patients. LN metastasis often happens through regional lymphatic system, leading to distal tumor formation including lungs, liver and bones. Successful imaging of small and microscopic LN metastasis provides the helpful information in deciding the therapeutic option of...
As sensitive magnetic sensors, superconducting quantum interference devices (SQUIDs) can be applied to measure weak magnetic field signals. Biomagnetism, measurement of magnetic signals from human body, especially at low frequency range below few kHz, is one of the important applications of SQUIDs, and biomagnetic technology can be applied for the functional study of human brain and heart. KRISS has...
A novel multiplexed sensing scheme based on Brownian relaxation for biomolecules tagged to magnetic nanoparticles (MNPs) in liquid environment is proposed. Feasibility of the technique has been verified by the experiments with the mixture of differently sized magnetic nanoparticles using a newly developed room temperature, miniaturized AC magnetic susceptometer. The AC magnetic susceptibility measurements...
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