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OCT has become already a standard diagnostic tool in ophthalmology. Despite its continuous improvement in performance, its tissue specificity is still limited, as the contrast mechanism relies on local backscattering changes only. Functional extensions of OCT, in particular Doppler OCT and angiography partially mitigate this limitation. Doppler OCT provides quantitative blood flow in a depth‐localized...
We develop an information-theoretic framework for the quantitative assessment of the maximum amount of information provided by optical coherence imaging through scattering media. We use our approach to investigate the fundamental dependence of the extractable information on the nature of the coherent imaging process, such as on speckle formation. We present nontrivial predictions for the maximum amount...
New phase-shifting techniques have recently been proposed to suppress the complex-conjugate ambiguity in frequency- domain optical-coherence tomography. A phase shift is introduced, in an elegant fashion, by incorporating a small beam offset at the scanning mirror. The tomogram is then computed by using a combination of Hilbert and Fourier transforms. This is a marked deviation from the conventional...
There is no doubt that optical coherence tomography has become an important biomedical imaging tool today especially due to recent improvements in detection as well as light source technology. OCT achieves resolution in tissue of a few micrometers and can thus seen as the missing link between full body tomography methods such as CT and MRI on the one hand and microscopy on the other side. We give...
We address the problem of exact signal recovery in frequency domain optical coherence tomography (FDOCT) systems. Our technique relies on the fact that, in a spectral interferometry setup, the intensity of the total signal reflected from the object is smaller than that of the reference arm. We develop a novel algorithm to compute the reflected signal amplitude from the interferometric measurements...
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