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On observe de l’ordre de 6000 cas en France de surdités brusques et quelques cas de surdité iatrogéniques, l’ensemble de ces cas étant accompagné d’acouphènes. Actuellement, la prise en charge des acouphènes chroniques repose en premier lieu sur le développement naturel ou facilité de l’habituation. Le recours à divers médicaments (vasodilatateurs, anxiolytiques, antidépresseurs) reste classique....
Tinnitus, also called phantom auditory perception, is a major health problem in western countries. As such, a significant amount of effort has been devoted to understanding its mechanisms, including studies in animals wherein a supposed “tinnitus state” can be induced. Here, we studied on the same awake animals the effects of a high-dose of salicylate and of an acoustic trauma both at levels known...
In this paper, we propose a method for detecting alterations in the Ensemble Spontaneous Activity (ESA), a random signal representing the composite spontaneous contribution of the auditory nerve recorded on the round window. The proposed method is based on shape analysis of the ESA amplitude histogram. For this task, we use a recent approach, the Corrected Integral Shape Averaging (CISA). Using this...
Average spectrum of electrophysiological cochlear activity (ASECA) recorded from the cochlea or the eighth nerve is related to firing of auditory neurons and has been recently in search of an objective measure of tinnitus both in animal models and in humans. Little is known about neuro-sensory processes underlying the spectral features of ASECA. The present study used awake and/or anesthetized animals...
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