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The nocturnal decline of blood pressure (BP) is almost coincident with the elevation of melatonin, which may exert vasodilatating and hypotensive effects. In this study we investigated whether prolonged nocturnal administration of melatonin could influence the daily rhythm of BP in women. In a randomized double-blind study, 18 women, 47 to 63 years of age and with normal BP (N = 9) or treated essential...
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