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Expression of P16 and MPO (myeloperoxidase) has been proposed as a marker for malignant transformation. In MPO, a G/A polymorphism at 463 bp upstream of the transcription start site of the enzyme has functional outcome, where G allele results in higher level of MPO expression than A allele. Protein P16, a key regulator in cell cycle, is also commonly associated with cancer. SNP of P16 exon3 (C540G)...