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Protein abundance determination across multiple samples proved to be a daunting task and far fewer methods have been successfully devised for this purpose. Despite the technical challenges faced, protein abundance determination over multiple samples is still an area of interest. Herein, we introduce a new method for estimation of protein abundances in multiplexed samples (PAMUS). Protein abundance...
Administration of sulfamethazine (300 mg/kg, i.p., single dose) to phenobarbital (80 mg/kg, i.p., 3 days) pretreated rats showed significant decrease in microsomal protein, electron transport components and drug metabolizing enzyme activities, compared with phenobarbital administration alone. Induction of mixed function oxidase enzymes due to phenobarbital was not affected by the pretreatment of...
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