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The cell adhesion molecule N-cadherin is involved in several processes during central nervous system development, but also in certain pathologic conditions in the adult brain, including tumorigenesis and Alzheimer's disease. N-cadherin function in inflammatory demyelinating disease has so far not been investigated. In vitro studies suggest a role of N-cadherin in myelination; on the other hand N-cadherin...
Entzündlich-rheumatische Erkrankungen können neben den bekannten muskuloskelettalen Manifestationen auch das zentrale und periphere Nervensystem betreffen. Die möglichen Symptome sind dabei genauso vielfältig wie die Krankheitsmechanismen, die sie hervorrufen können. Eine rasche diagnostische Abklärung, die Einleitung einer adäquaten Therapie und ein regelmäßiges Monitoring dieser Patienten sind notwendig,...
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