The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
(−)-Renieramycin G was synthesized in 21 steps for the longest linear sequences employing l-tyrosine methyl ester as the chiral starting material in 8.5% overall yield. Two of the four chiral centers came from l-tyrosine methyl ester, and the other two were induced through an intermolecular and an intramolecular Pictet–Spengler reaction, respectively.
An isoquinoline-3-carboxylate compound 3 was obtained with a moderate yield of 40% when N-acetyl-(3′-hydroxy-4′-methoxy-5′-methyl)phenylalanine methyl ester 1 was refluxed in HMTA/TFA. However, the anticipated product N-acetyl-(3′-hydroxy-4′-methoxy-5′-methyl-6′-formyl)phenylalanine methyl ester 2 could not be found. The possible mechanism was discussed in this article.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.