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The paranasal sinus epithelium is exposed to the environment and therefore to a variety of biological, chemical and mechanical insults. Surfactant protein A (SP-A) is a 34–36 kD pulmonary surfactant-associated protein that appears to play an important role in mammalian first-line host defence. Recent studies have reported the possibility of local production of SP-A in the extrapulmonary organs and...
It is unclear why the prescription of lipid lowering therapy (rx) is low in patients (pts) with coronary artery disease (CAD). We examined an administrative data set containing chart audits on 125,433 outpts with CAD (ICD9 code 410-414) from 274 US cardiology and multispecialty practices to determine the predictors of the prescription of rx. After exclusions due to incomplete data or lack of consent,...
A role of prostaglandins (PGs) and leukotrienes (LTs) in the pathogenesis of nasal polyps has been recently suggested. Cyclooxygenase (CO) products (thromboxane B 2 , PGE 2 and 6-keto PGF 1 alpha) and lipoxygenase (LO) products (LTB 4 and LTC 4 ) were investigated by radioimmunoassay in polyps, hypertrophic turbinates and nasal mucosa from 14 patients with non-allergic...
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