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ObjectiveTo evaluate the efficacy, tolerability, and safety of once‐daily 1200 mg and 2400 mg SPN‐804 (Oxtellar XR™, Supernus Pharmaceuticals), an extended‐release tablet formulation of oxcarbazepine (OXC), added to 1‐3 concomitant antiepileptic drugs (AEDs) in adults with refractory partial‐onset seizures, with or without secondary generalization.
MethodsThe Prospective, Randomized Study of OXC...
Status epilepticus (SE) is a common, serious, potentially life-threatening, neurologic emergency characterized by prolonged seizure activity. Generalized convulsive status epilepticus (GCSE) is the most widely recognized form of SE. Direct consequences of convulsive movements from SE can result in injury to the body and brain. Nonconvulsive status epilepticus (NCSE) is underrecognized, with controversy...
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