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In this paper, we conducted to assembly of microstructures for in vitro 3D cellular structures using self-assembly of magnetized hydrogels. The biocompatible hydrogel microstructures are fabricated by electrodeposition method and ferrite particles are coated on the structures with poly-L-lysine. The microstructures are magnetized by applying 3 T magnetic field, and assembled by the magnetic force...
In this paper, we conducted a new method to assemble microstructures inside a droplet named “Lab in a Droplet (LiD)”. The method can realize the assembly of micro-nano structures inside a droplet size. The surface tension is used to assemble microstructures automatically. Micro-scale or nano-scale objects are ejected from an inkjet nozzle. They are gathered at the center of the droplet and assembled...
Cellular vascular-like microtubes occupy an important position in tissue engineering for building in vitro tissue models. In this paper, we report a method of constructing three-dimensional (3D) multilayered vascular-like microtubes based on fluidic axis-translation self-assembly of two-dimensional (2D) microstructures inside microfluidic devices. The on-chip fabrication of cell (fibroblasts NIH/3T3)...
We propose a new concept “Lab in a Droplet (LiD)” as a micro to nano scale self-assembly technique. The liquid bridge force is used for assembly of microstructures automatically. Micro/nano objects are ejected from an inkjet nozzle and they are automatically assembled inside a droplet by the liquid bridge force. In this paper, we conducted preliminary experiment to check the possibility of LiD. The...
Microfluidic devices provide efficient approaches for building cellular tubular structures for in vitro tissue models in tissue engineering. In this paper, we report a novel method of constructing three-dimensional (3D) multilayered tubular structures based on axis translation of two-dimensionally (2D) microstructures inside microfluidic devices. The on-chip fabrication of movable 2D microstructures...
Microfluidic devices provide efficient approaches for building bio-mimetic tubular structures for in vitro tissue models. In this paper, we report a novel method of constructing multilayered tubular structures embedding cells via a 2-layer microfluidic device. The on-chip fabrication of movable microstructures embedding fibroblasts (NIH/3T3) based on Poly (ethylene glycol) Diacrylate (PEGDA) was reported...
Microfluidic devices provide efficient approaches for building bio-mimetic tube-shaped structures for tissue engineering or in vitro tissue models. We report a novel method of constructing multi-layered tube-shaped microstructures embedding cells via a 2-layer microfluidic device. The on-chip fabrication of movable microstructures embedding fiber blast cell (NIH/3T3) based on Poly (ethylene glycol)...
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