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•Leptin, α-MSH and PYY has an intrinsic action stimulating the anorexigenic pathways in a post RYGB.•Anorexigenic pathways may play a prominent role in the effectiveness of the RYGB.•The central melanocortin system may be a key role in sustained long-term weight loss.•α-MSH contributes to weight loss by stimulate lipolysis and adipose tissue browning.•Compensatory hormonal adaptation leads to increased...
Significant changes in the preference for different dietary components have been observed after Roux-en-Y gastric bypass (RYGB). The aim of this study was to evaluate the early post-RYGB changes in quality of eating patterns and their relationship to weight loss and metabolic parameters.The sample was composed of 41 extremely obese individuals undergoing RYGB. Dietary data were collected using a validated...
Background The low-grade inflammatory state in obesity leads to insulin resistance and endothelial dysfunction, which promote cardiovascular diseases in individuals with obesity. The purpose of this study was to evaluate the early effects of weight loss achieved through bariatric surgery on the inflammatory and prothrombotic states. This study also aimed to identify the role of hyperleptinemia on...
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