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To evaluate whether ET secreted from keratinocytes under the UV irradiation works as paracrine effects such as melanocyte proliferation and function, the present study was undertaken. Cultured human keratinocytes were irradiated with UUVB 50mJ/cm 2 . Twenty fours hours later, conditioned medium of keratinocytes was added into the growth medium of melanocytes. Four days later, in order to...