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The rigorous characterization of distinct induced pluripotent stem cells (iPSC) derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability and downstream potential. To achieve this goal, the Progenitor Cell Biology Consortium performed comprehensive experimental and genomic analyses of 58 iPSC from ten laboratories generated...
In this work, we apply the projection-based model-reduction framework for PDEs of [1] to the diffusion process governing the intercalation of lithium ions into spherical particles that appears in electrochemical models of Li-ion batteries. We first invoke the projection framework with different projections (the so-called natural—i.e. Galerkin—and volume-averaging projections—NP and VAP, respectively)...
Wnt signaling plays important roles in embryonic development, tissue differentiation, and cancer [1–7]. In both normal and malignant tissue, Wnt family members are often expressed combinatorially [8–11], although the significance of this is not understood. We recently showed that Wnt11 and Wnt5a are both required for the initiation of embryonic axis formation and that the two proteins physically interact...
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