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Abnormal proliferations of the endometrium form a morphological continuum ranging from simple glandular hyperplasia to frankly invasive cancer. The extremes of this spectrum of pathology are relatively easily identified and treated. It is the intermediate, varying degrees of closely packed complex glands with cytological atypia that present the most difficulty with regard to diagnosis, and subsequent...
To test the antitumor effect of gonadotrophin-releasing hormone (GnRH) analogs, 32 consecutive patients with recurrent endometrial cancer that had progressed through conventional treatments were entered into an open observational trial of treatment with this class of compounds. Patients recruited had progressive, symptomatic, and measurable disease. Treatment was with monthly subcutaneous injections...
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