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Background: ACC/ASNC guidelines recommend vasodilator stress for the diagnosis and risk stratification of patients with left bundle branch block (LBBB) regardless of exercise capacity. There are no data comparing exercise and vasodilator gated stress myocardial perfusion imaging (MPI) for risk stratification of patients with LBBB.Methods: A consecutive series of 418 patients with LBBB underwent exercise...
To evaluate the effect of the vasodilator stress agent upon defect size, 30 patients with known coronary artery disease underwent rest, adenosine (AD 0.84 mg/kg over 6 minutes) and dipyridamole (DIP 0.56 mg/kg over 4 minutes) stress testing with Tc-99m tetrofosmin (25-30 mCi) SPECT imaging on separate days. All images were interpreted by 3 nuclear cardiologists without knowledge of patient identity...
Differences in tracer kinetics between Tc-99m tetrofosmin (TETRO) and Tc-99m sestamibi (MIBI) may result in smaller defects on exercise SPECT imaging with TETRO. To address this issue, we performed rest and standard Bruce protocol exercise with SPECT myocardial perfusion imaging with both TETRO and MIBI on two separate visits in 19 men with known coronary disease. Each imaging agent was injected...
ECG-gated SPECT imaging (GSI) using Tc-99m myocardial perfusion agents permits visual assessment of wall motion (WM) as well as quantitative calculation of LV ejection fraction (EF) and is most useful in patients with LV dysfunction. Little data correlating WM and quantitative EF is available in this population. Therefore 34 patients with dilated cardiomyopathy (23 non-ischemic, 11 ischemic) and...
To evaluate the role of low dose dobutamine infusion (LDD) during the count acquisition using resting Technetium-99m sestamibi ECG gated SPECT imaging (GSI) in the prediction of myocardial viability, 12 patients with left ventricular dysfunction scheduled for revascularization underwent GSI before and during LDD. GSI was repeated at 1 and 6 weeks after revascularization. The images were interpreted...
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