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The International Space Station will carry the external facility EXPOSE for exobiological studies under free space conditions and/or selected space parameters. Complementary to such experimentation in space, a profound ground support program under simulated space conditions is required: (i) to support the scientific EXPOSE community in the definition of the experiments under simulated space conditions;...
In the present investigation we report the effects of simulated microgravity conditions (clinostat) on the induction of chromosomal aberrations in human lymphocytes in vitro by (R)Bleomycin. Chromosomal aberrations have been analysed by means of fluorescent in situ hybridisation (FISH) and chromosome-specific composite DNA probes (chromosome painting).The results obtained show that, under simulated...
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