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The relationship between bone and the kidney in renal osteodystrophy is a complex interplay of kidney to bone connections, bone to kidney connections, and cell to cell connections. In addition, such interactions have a profound effect on the vasculature. In this review, we discuss the role of the bone morphogenetic proteins (BMPs) in the skeleton, kidney, and vasculature. In addition, we propose that...
The purpose of this study was to determine whether the production of interstitial collagenase mRNA in response to parathyroid hormone (PTH) changes with osteoblast phenotypic development. To accomplish this, cells derived from fetal rat calvaria were examined. The calvarial osteoblasts, which proliferate when placed in culture, can be made to differentiate after confluence. Studies were performed...
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