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BACKGROUNDIn the Chenopodiaceae family, the apigenin flavonoids vitexin‐2‐O‐xyloside (VOX) and vitexin‐2‐O‐rhamnoside (VOR) are important chemopreventive components. To investigate their bioavailability in in vivo animal studies an enzyme‐linked immunosorbent assay (ELISA) method has been developed.
RESULTSThe ELISA was based on polyclonal antibodies elicited in mice by injecting, as an immunogen,...
We have previously demonstrated that in Ova-immunized mice the increase in intra-macrophage thiol pool induced by pro-GSH molecules modulates the Th1/Th2 balance in favour of a Th1-type immune response. We show now that the same molecules can support a Th1-type over Th2-type immunity against Tat, which is an early HIV-1 regulatory protein and a Th1 polarizing immunomodulator that is increasingly considered...
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