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Tiotropium Respimat® improved lung function in a phase 2 trial in patients with cystic fibrosis (CF). We investigated its efficacy and safety in a phase 3 trial, including a pre-specified pooled analysis of the phase 2 and 3 trials.12-week, randomized, double-blind, placebo-controlled trial of tiotropium Respimat® 5μg once daily in patients with CF (N=463).Co-primary efficacy endpoints showed no statistical...