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Although countless highly penetrant variants have been associated with Mendelian disorders, the genetic etiologies underlying complex diseases remain largely unresolved. By mining the medical records of over 110 million patients, we examine the extent to which Mendelian variation contributes to complex disease risk. We detect thousands of associations between Mendelian and complex diseases, revealing...
Veterinary medicine and human health are inextricably intertwined. Effective tracking of veterinary information – veterinary informatics – impacts not only veterinary medicine, but also public health, informatics research, and clinical care. However, veterinary informatics has received little attention from the general biomedical informatics community.To identify both active and under-researched areas...
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