T.C. Sorrell

article

Identification of genetic markers of resistance to echinocandins, azoles and 5-fluorocytosine in Candida glabrata by next-generation sequencing: a feasibility study

C. Biswas, S.C.-A. Chen, C. Halliday, K. Kennedy, more

Clinical Microbiology and Infection > 2017 > 23 > 9 > 676.e7-676.e10

Multi-antifungal drug resistance in Candida glabrata is increasing. We examined the feasibility of next-generation sequencing (NGS) to investigate the presence of antifungal drug resistance markers in C. glabrata.The antifungal susceptibility of 12 clinical isolates and one ATCC strain of C. glabrata was determined using the Sensititre YeastOne^® YO10 assay. These included three isolate pairs where...

article

Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality

M. Slavin, S. van Hal, T.C. Sorrell, A. Lee, more

Clinical Microbiology and Infection > 2015 > 21 > 5 > 490.e1-490.e10

The epidemiology of invasive fungal disease (IFD) due to filamentous fungi other than Aspergillus may be changing. We analysed clinical, microbiological and outcome data in Australian patients to determine the predisposing factors and identify determinants of mortality. Proven and probable non-Aspergillus mould infections (defined according to modified European Organization for Research and Treatment...

article

Clinical features of endemic community-acquired psittacosis

J.M. Branley, K.M. Weston, J. England, D.E. Dwyer, more

New Microbes and New Infections > 2014 > 2 > 1 > 7-12

Following a large outbreak of community-acquired psittacosis in 2002 in residents of the Blue Mountains, New South Wales, Australia, we reviewed new cases in this area over a 7-year period from 2003 to 2009. Using the 2010 criteria from the Centers for Disease Control National Notifiable Diseases Surveillance System, 85 patients with possible psittacosis were identified, of which 48 were identified...

article

Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients

P.E. Ferguson, N.M. Gilroy, T.P. Sloots, M.D. Nissen, more

Transplant Infectious Disease > 13 > 5 > 448 - 455

P.E. Ferguson, N.M. Gilroy, T.P. Sloots, M.D. Nissen, D.E. Dwyer, T.C. Sorrell. Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients. Transpl Infect Dis 2011: 13: 448–455. xx: 000–000. All rights reserved Abstract: A simple clinical screening (CS) tool for respiratory virus (RV) infection was introduced...

article

CS3.3 Recent advances in management of cryptococcal meningitis

T.C. Sorrell

International Journal of Infectious Diseases > 2011 > 15 > Supplement 1 > S2

article

Skull-base osteomyelitis: fungal vs. bacterial infection

C.C. Blyth, L. Gomes, T.C. Sorrell, M. da Cruz, more

Clinical Microbiology and Infection > 2011 > 17 > 2 > 306-311

Skull-base osteomyelitis (SBO) occurs secondary to invasive bacterial and fungal infection. Distinguishing between fungal and bacterial aetiologies of SBO has significant therapeutic implications. An 18-year (1990–2007) retrospective review of patients with SBO presenting to Westmead Hospital was performed. Epidemiological, clinical, laboratory and radiology data were collated. Twenty-one patients...

article

Erratum to: Echinocandin antifungal drugs in fungal infections: a comparison

SC-A Chen, Ma Slavin, Tc Sorrell

Drugs > 2011 > 71 > 2 > 253-253

The original online version for this chapter can be found at http://dx.doi.org/10.2165/11585270-000000000-00000

article

Increasing incidence of candidaemia: long-term epidemiological trends, Queensland, Australia, 1999–2008

E.G. Playford, G.R. Nimmo, M. Tilse, T.C. Sorrell

Journal of Hospital Infection > 2010 > 76 > 1 > 46-51

Given variability in the epidemiology of candidaemia and a relative paucity of contemporary longitudinal data, a passive laboratory-based surveillance study was performed to assess the epidemiology of candidaemia in all public healthcare facilities in Queensland, Australia over the period 1999–2008. Demographic and microbiological data on all candidaemia episodes, together with appropriate denominators...

article

Candidaemia with uncommon Candida species: predisposing factors, outcome, antifungal susceptibility, and implications for management

S.C.A. Chen, D. Marriott, E.G. Playford, Q. Nguyen, more

Clinical Microbiology and Infection > 2009 > 15 > 7 > 662-669

The risk factors for and clinical features of bloodstream infection with uncommon Candida spp. (species other than C. albicans, C. glabrata, C. parapsilosis, C. tropicals and C. krusei) are incompletely defined. To identify clinical variables associated with these species that might guide management, 57 cases of candidaemia resulting from uncommon Candida spp. were analysed in comparison with 517...

article

Population-based surveillance for scedosporiosis in Australia: epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection

C.H. Heath, M.A. Slavin, T.C. Sorrell, R. Handke, more

Clinical Microbiology and Infection > 2009 > 15 > 7 > 689-693

Australia-wide population-based surveillance for scedosporiosis identified 180 cases, with 118 (65.6%) cases of colonization and 62 (34.4%) cases of infection. Predisposing factors for isolation of Scedosporium spp. included chronic lung disease in 37.8% and malignancy in 21.7% of cases. Predictors of invasive disease (n = 62) included haematological stem cell transplantation (n = 7), leukaemia (n...

article

New Generation Triazoles: What Do They Offer and When Do We Need Them?

T.C. Sorrell

International Journal of Infectious Diseases > 2008 > 12 > Supplement 1 > e12

article

Unsupervised feature dimension reduction for classification of MR spectra

R. Baumgartner, R. Somorjai, C. Bowman, T.C. Sorrell, more

Magnetic Resonance Imaging > 2004 > 22 > 2 > 251-256

We present an unsupervised feature dimension reduction method for the classification of magnetic resonance spectra. The technique preserves spectral information, important for disease profiling. We propose to use this technique as a preprocessing step for computationally demanding wrapper-based feature subset selection. We show that the classification accuracy on an independent test set can be sustained...

article

Cryptococcus neoformans var. gattii infection in northern Australia: existence of an environmental source other than known host eucalypts

S.C.A. Chen, B.J. Currie, H.M. Campbell, D.A. Fisher, more

Transactions of the Royal Society of Tropical Medicine and Hygiene > 1997 > 91 > 5 > 547-550

The 2 known host trees of Cryptococcus neoformans var. gattii, Eucalyptus camaldulensis and E. tereticornis, do not occur naturally in the 'Top End' of the Northern Territory (NT) of Australia. Nine clinical isolates of C. neoformans var. gattii from the NT were analysed by random amplification of polymorphic deoxyribonucleic acid (rapd) and polymerase chain reaction 'fingerprinting'.Two isolates...

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Search results for: T.C. Sorrell

Identification of genetic markers of resistance to echinocandins, azoles and 5-fluorocytosine in Candida glabrata by next-generation sequencing: a feasibility study

Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality

Clinical features of endemic community-acquired psittacosis

Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients

CS3.3 Recent advances in management of cryptococcal meningitis

Skull-base osteomyelitis: fungal vs. bacterial infection

Erratum to: Echinocandin antifungal drugs in fungal infections: a comparison

Increasing incidence of candidaemia: long-term epidemiological trends, Queensland, Australia, 1999–2008

Candidaemia with uncommon Candida species: predisposing factors, outcome, antifungal susceptibility, and implications for management

Population-based surveillance for scedosporiosis in Australia: epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection

New Generation Triazoles: What Do They Offer and When Do We Need Them?

Unsupervised feature dimension reduction for classification of MR spectra

Cryptococcus neoformans var. gattii infection in northern Australia: existence of an environmental source other than known host eucalypts

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