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As an effective method to explore the interaction mechanism between aggregate particles and geogrids, a large-scale direct shear test was employed to study the shear behavior of aggregate-geogrid interface and the effects of particle size on the interfacial shear strength. Two types of geogrids with rectangular or triangular aperture and three single-sized coarse aggregates, 12.5–19 mm, 19–25 mm,...
We report that disruption of CD154 in nonobese diabetic (NOD) mice abrogates the helper function of CD4 + CD25 - T cells without impairing the regulatory activity of CD4 + CD25 + T cells. Whereas CD4 + T cells from NOD mice enhanced a diabetogenic CD8 + T cell response in monoclonal TCR-transgenic NOD mice, CD4 + T cells from NOD.CD154 -...
We followed the fate of K d - or I-A g7 -restricted β cell-autoreactive T cells in monoclonal TCR-transgenic NOD mice expressing or lacking CD154. 8.3-NOD.RAG-2 -/- /CD154 -/- mice, which bear autoreactive CD8 + T cells, developed diabetes with the same incidence and tempo as 8.3-NOD.RAG-2 -/- /CD154 + mice...
Extracts from shiitake (Lentinula edodes) mycelial culture broth, by an organic solvent ethyl acetate, inhibited the proliferation of cultured cells. At lower concentrations (1.25-15μg/ml), this inhibition, measured by the MTT assay, was dose- and cell line-dependent, inhibition of tumor cells, such as Caski, SiHa, HeLa, HP-1 and A375, by L. edodes- 436 extracts was stronger than inhibition of normal...
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