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Glioblastoma (GBM) occurs more commonly in elderly patients. However, these patients are often excluded from clinical trials. The absence of solid evidence has resulted in a nihilistic view of GBM in the elderly and a traditionally conservative treatment approach. In particular, the safety of surgical resection for both primary and recurrent GBM is poorly understood in elderly patients.In a retrospective...
There are two hypotheses for the primary function of the T H /IgE system: protection against helminths that 'spills over' into inappropriate allergic responses in the modern environment, or protection from a variety of environmental carcinogens and infectious diseases that is adaptive even today. We suggest that rather than being alternatives, these two hypotheses fit into a single causal...
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