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Nanoparticle tracking analysis (NTA) is commonly used to count and size nano-sized particles. A sample loading pump can be used to analyse a larger sample volume, but it is unclear whether accuracy is affected. Using a NanoSight NS300 with the manufacturer-supplied pump, we examined synthetic silica and latex microspheres, liposomes and placental extracellular vesicles at different flow speeds. Analysis...
Mitochondrial DNA mutations cause disease in >1 in 5000 of the population, and ∼1 in 200 of the population are asymptomatic carriers of a pathogenic mtDNA mutation. Many patients with these pathogenic mtDNA mutations present with a progressive, disabling neurological syndrome that leads to major disability and premature death. There is currently no effective treatment for mitochondrial disorders,...
To describe the UK Food Surveillance System (FSS UK) currently in operation in Scotland and Northern Ireland, and being introduced UK-wide, particularly in relation to the development, scope and roll-out of the system.Pilot questionnaire, followed by pilot information technology (IT)-based study and subsequent roll-out.A paper-based trial of data collection was introduced, followed by an IT-based...
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