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Key points
Carbon dioxide levels are mildly elevated on the International Space Station and it is unknown whether this chronic exposure causes physiological changes to astronauts.
We combined ∼4 mmHg ambient with the strict head‐down tilt bed rest model of spaceflight and this led to the development of optic disc oedema in one‐half of the subjects.
We demonstrate no change in arterialized...
Exercise deconditioning during space flight may impact a crewmember's ability to perform strenuous or prolonged tasks during and after a spaceflight mission. In this paper, we review the cardiovascular exercise data from U.S. spaceflights from the Mercury Project through International Space Station (ISS) expeditions and potential implications upon current and future missions. During shorter spaceflights...
Bone loss associated with disuse during bed rest (BR), an analog of space flight, can be attenuated by exercise. In previous studies, the efficacy of either aerobic or resistive exercise countermeasures has been examined separately. We hypothesized that a regimen of combined resistive and aerobic exercise during BR would prevent bone resorption and promote bone formation. After a 20-day ambulatory...
Supine weight-bearing exercise within lower body negative pressure (LBNP) alleviates some of the skeletal deconditioning induced by simulated weightlessness in men. We examined this potential beneficial effect in women. Because dietary acid load affected the degree of bone resorption in men during bed rest, we also investigated this variable in women. Subjects were 7 pairs of female identical twins...
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